Functional Homologous Recombination Assay on FFPE Specimens of Advanced High-Grade Serous Ovarian Cancer Predicts Clinical Outcomes

Pikkusaari, S; Tumiati, M; Virtanen, A; Oikkonen, J; Li, YL; Perez-Villatoro, F; Muranen, T; Salko, M; Huhtinen, K; Kanerva, A; Koskela, H; Tapper, J; Koivisto-Korander, R; Joutsiniemi, T; Haltia, UM; Lassus, H; Hautaniemi, S; Färkkilä, A; Hynninen, J; Hietanen, S; Carpén, O; Kauppi, L

Kauppi, L (通讯作者)，Univ Helsinki, POB 63 Haartmaninkatu 8, FI-00014 Helsinki, Finland.

CLINICAL CANCER RESEARCH, 2023; 29 (16): 3110

Abstract

Purpose:Deficiency in homologous recombination (HR) repair of DNA damage is characteristic of many high-grade serous ovarian cancers (HGSC). It is imp......

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