Are the N-demethylated metabolites of U-47700 more active than their parent compound? In vitro mu-opioid receptor activation of N-desmethyl-U-47700 and N,N-bisdesmethyl-U-47700

Nordmeier, F; Cannaert, A; Stove, CP; Schmidt, PH; Meyer, MR; Schaefer, N

Schaefer, N (通讯作者)，Saarland Univ, Inst Legal Med, Homburg, Germany.

DRUG TESTING AND ANALYSIS, 2022; 14 (4): 713

Abstract

Studies on the tissue distribution of the new synthetic opioid U-47700 and its main metabolite N-desmethyl-U-47700 revealed about sixfold higher metab......

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