Mitochondrial ROS-mediated ribosome stalling and GCN2 activation are partially involved in 1-nitropyrene-induced steroidogenic inhibition in testes

Li, J; Gao, L; Chen, J; Zhang, WW; Zhang, XY; Wang, B; Zhang, C; Wang, Y; Huang, YC; Wang, H; Wei, W; Xu, DX

Gao, L; Xu, DX (通讯作者)，Anhui Med Univ, Key Lab Environm Toxicol, Anhui Higher Educ Inst, Hefei 230032, Peoples R China.;Wei, W (通讯作者)，Anhui Med Univ, Key Lab Antiinflammatory & Immune Med, Educ Minist China, Hefei 230032, Peoples R China.

ENVIRONMENT INTERNATIONAL, 2022; 167 ():

Abstract

In the past 50 years, testosterone (T) level in men has declined gradually. In this research, we discovered that acute exposure to 1-nitropyrene (1-NP......

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