Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts

Ellegast, JM; Alexe, G; Hamze, A; Lin, S; Uckelmann, HJ; Rauch, PJ; Pimkin, M; Ross, LS; Dharia, NV; Robichaud, AL; Conway, AS; Khalid, D; Perry, JA; Wunderlich, M; Benajiba, L; Pikman, Y; Nabet, B; Gray, NS; Orkin, SH; Stegmaier, K

Stegmaier, K (通讯作者),Dana Farber Canc Inst, 360 Longwood Ave, Boston, MA 02215 USA.

CANCER DISCOVERY, 2022; 12 (7): 1760

Abstract

Leukemic blasts are immune cells gone awry. We hypothesized that dysregulation of inflammatory pathways contributes to the maintenance of their leukem......

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