Cytoplasmic PARP-1 promotes pancreatic cancer tumorigenesis and resistance

Xu, F; Sun, Y; Yang, SZ; Zhou, T; Jhala, N; McDonald, J; Chen, YB

Chen, YB (reprint author), Univ Alabama Birmingham, Dept Pathol, 614 Shelby Res Bldg,1825 Univ Blvd, Birmingham, AL 35294 USA.

INTERNATIONAL JOURNAL OF CANCER, 2019; 145 (2): 474

Abstract

The poly(ADP-ribose) polymerases (PARP) play important roles in repairing damaged DNA during intrinsic cell death. We recently linked PARP-1 to death ......

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