DNA hydroxymethylation increases the susceptibility of reactivation of methylated P16 alleles in cancer cells

Li, PY; Gan, Y; Qin, SS; Han, X; Cui, CH; Liu, ZJ; Zhou, J; Gu, LK; Lu, ZM; Zhang, BZ; Deng, DJ

Zhang, BZ; Deng, DJ (reprint author), Peking Univ, Canc Hosp & Inst, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Div Etiol, Fu Cheng Lu 52, Beijing 100142, Peoples R China.

EPIGENETICS, 0; ():

Abstract

It is well established that 5-methylcytosine (5mC) in genomic DNA of mammalian cells can be oxidized into 5-hydroxymethylcytosine (5hmC) and other der......

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