Proliferative CD8(+) PD-1(+) T-cell infiltration in a pembrolizumab-induced cutaneous adverse reaction

Kunimasa, K; Isei, T; Nakamura, H; Kimura, M; Inoue, T; Tamiya, M; Nishino, K; Kumagai, T; Nakatsuka, S; Endo, H; Inoue, M; Imamura, F

Kunimasa, K (reprint author), Osaka Int Canc Inst, Dept Thorac Oncol, Chuo Ku, 3-1-69 Otemae, Osaka 5418567, Japan.

INVESTIGATIONAL NEW DRUGS, 2018; 36 (6): 1138

Abstract

Pembrolizumab, a humanized monoclonal immunoglobulin (Ig) G4 antibody that is directed against the human cell surface receptor PD-1, is a PD-1 pathway......

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