Ultraviolet photodissociation of fondaparinux generates signature antithrombin-like 3-O-sulfated-GlcNS3S6S-monosaccharide fragment (Y-3/C-3)

Hawkridge, AM; Hackbusch, S

Hawkridge, AM (corresponding author), Virginia Commonwealth Univ, Sch Pharm, Dept Pharmaceut & Pharmacotherapy & Outcomes Sci, Med Coll Virginia Campus, Richmond, VA 23298 USA.; Hawkridge, AM (corresponding author), Virginia Commonwealth Univ, Inst Struct Biol Drug Discovery & Dev, Med Coll Virginia Campus, Richmond, VA 23298 USA.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020; 412 (28): 7925

Abstract

The 3-O sulfate-modified -GlcNS3S6S- monosaccharide in heparin and heparan sulfate glycosaminoglycans (HSGAGs) is a relatively rare yet important modi......

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