The Proteolytic Inactivation of Protein Z-Dependent Protease Inhibitor by Neutrophil Elastase Might Promote the Procoagulant Activity of Neutrophil Extracellular Traps in Sepsis

Bianchini, EP; Razanakolona, M; Helms, J; Zouiti, F; Couteau-Chardon, A; Marin-Esteban, V; de Chaisemartin, L; De-Carvalho, A; Bironien, R; Chollet-Martin, S; Denis, CV; Diehl, JL; Vasse, M; Meziani, F; Borgel, D

Bianchini, EP (通讯作者),INSERM U1176, 80 Rue Gen Leclerc, F-94276 Le Kremlin Bicetre, France.

THROMBOSIS AND HAEMOSTASIS, 2022; 122 (4): 506

Abstract

Septic shock is the archetypal clinical setting in which extensive crosstalk between inflammation and coagulation dysregulates the latter. The main an......

Full Text Link