Validity of polygenic risk scores: are we measuring what we think we are?

Janssens, ACJW

Janssens, ACJW (reprint author), Emory Univ, Rollins Sch Publ Hlth, Dept Epidemiol, 1518 Clifton Rd NE, Atlanta, GA 30322 USA.

HUMAN MOLECULAR GENETICS, 2019; 28 (R2): R143

Abstract

Polygenic risk scores (PRSs) have become the standard for quantifying genetic liability in the prediction of disease risks. PRSs are generally constru......

Full Text Link