Novel Mixed NOP/Opioid Receptor Peptide Agonists

Pacifico, S; Albanese, V; Illuminati, D; Marzola, E; Fabbri, M; Ferrari, F; Holanda, VAD; Sturaro, C; Malfacini, D; Ruzza, C; Trapella, C; Preti, D; Lo Cascio, E; Arcovito, A; Della Longa, S; Marangoni, M; Fattori, D; Nassini, R; Calo, G; Guerrini, R

Preti, D (corresponding author), Univ Ferrara, Dept Chem Pharmaceut & Agr Sci, I-44121 Ferrara, Italy.; Ruzza, C (corresponding author), Univ Ferrara, Dept Neurosci & Rehabil, Sect Pharmacol, I-44121 Ferrara, Italy.; Della Longa, S (corresponding author), Univ Aquila, Dept Life Hlth & Environm Sci, I-67100 Laquila, Italy.

JOURNAL OF MEDICINAL CHEMISTRY, 2021; 64 (10): 6656

Abstract

The nociceptin/orphanin FQ (N/OFQ)/N/OFQ receptor (NOP) system controls different biological functions including pain and cough reflex. Mixed NOP/opio......

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