Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling

Henry, WS; Laszewski, T; Tsang, T; Beca, F; Beck, AH; McAllister, SS; Toker, A

Toker, A (reprint author), Harvard Med Sch, Beth Israel Deaconess Med Ctr, 330 Brookline Ave,EC-CLS 633A, Boston, MA 02215 USA.

CANCER RESEARCH, 2017; 77 (3): 790

Abstract

Despite the high incidence of oncogenic mutations in PIK3CA, the gene encoding the catalytic subunit of PI3K, PI3K inhibitors have yielded little clin......

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