Berzosertib Plus Topotecan vs Topotecan Alone in Patients With Relapsed Small Cell Lung Cancer A Randomized Clinical Trial

Takahashi, N; Hao, ZL; Villaruz, LC; Zhang, J; Ruiz, J; Petty, WJ; Mamdani, H; Riess, JW; Nieva, J; Pachecho, JM; Fuld, AD; Shum, E; Chauhan, A; Nichols, S; Shimellis, H; Mcglone, J; Sciuto, L; Pinkiert, D; Graham, C; Shelat, M; Kattappuram, R; Abel, M; Schroeder, B; Upadhyay, D; Krishnamurthy, M; Sharma, AK; Kumar, R; Malin, J; Schultz, CW; Goyal, S; Redon, CE; Pommier, Y; Aladjem, MI; Gore, SD; Steinberg, SM; Vilimas, R; Desai, P; Thomas, A

Thomas, A (通讯作者)，NCI, Ctr Canc Res, Dev Therapeut Branch, Bldg 10,Room 4-5330, Bethesda, MD 20892 USA.

JAMA ONCOLOGY, 2023; 9 (12): 1669

Abstract

Importance Patients with relapsed small cell lung cancer (SCLC), a high replication stress tumor, have poor prognoses and few therapeutic options. A p......

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