Metabolism and Disposition of the Novel Oral Factor XIa Inhibitor Asundexian in Rats and in Humans

Piel, I; Engelen, A; Lang, DT; Schulz, SI; Gerisch, M; Brase, C; Janssen, W; Fiebig, L; Heitmeier, S; Kanefendt, F

Kanefendt, F (通讯作者),Clin Pharmacol, Bayer AG, D-42096 Wuppertal, Germany.

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2023; 48 (4): 411

Abstract

Background and Objectives Current anticoagulants pose an increased risk of bleeding. The development of drugs targeting factor XIa, like asundexian, m......

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