Efficacy and Safety of the Fixed-Dose Versus Variable-Dose of 4-PCC for Vitamin K Antagonist Reversal: A Comprehensive Systematic Review and Meta-Analysis

Mohammadi, K; Yaribash, S; Sani, MA; Talasaz, AH

Talasaz, AH (通讯作者)，Univ Tehran Med Sci, Dept Clin Pharm, Fac Pharm, Tehran, Iran.;Talasaz, AH (通讯作者)，Univ Tehran Med Sci, Tehran Heart Ctr, Tehran, Iran.

CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (3): 533

Abstract

Background The optimal dosing strategy of four-factor prothrombin complex concentrate (4F-PCC) for vitamin K antagonists (VKAs) reversal is unknown. M......

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