Diarylheptanoid 35d overcomes EGFR TKI resistance by inducing hsp70-mediated lysosomal degradation of EGFR in EGFR-mutant lung adenocarcinoma

Hong, X; Hsieh, MT; Tseng, TY; Lin, HY; Chang, HC; Yau, ST; Cheng, WC; Ke, BZ; Liao, HH; Wu, CY; Liu, AA; Wu, MM; Huang, KY; Yang, PC; Kuo, SC; Hung, MC; Lee, PC

Hung, MC; Lee, PC (通讯作者)，China Med Univ, Res Ctr Canc Biol, Taichung, Taiwan.;Hung, MC; Lee, PC (通讯作者)，China Med Univ, Grad Inst Biomed Sci, Taichung, Taiwan.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2023; 299 (6):

Abstract

Epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma (LUAD) patients often respond to EGFR tyrosine kinase inhibitors (TKIs) initially b......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索