Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species

Chang, XL.; Reed, JS; Webb, GM; Wu, HLL.; Le, JMY; Bateman, KB; Greene, JM; Pessoa, C; Waytashek, C; Weber, WC; Hwang, J; Fischer, M; Moats, C; Shiel, O; Bochart, RM; Crank, H; Siess, D; Giobbi, T; Torgerson, J; Agnor, R; Gao, LA; Dhody, K; Lalezari, JP; Bandar, IS; Carnate, AM; Pang, ALAS.; Corley, MJ; Kelly, S; Pourhassan, N; Smedley, J; Bimber, BN; Hansen, SG; Ndhlovu, LC; Sacha, JB

Sacha, JB (通讯作者)，Oregon Hlth & Sci Univ, Vaccine & Gene Therapy Inst, Portland, OR USA.;Sacha, JB (通讯作者)，Oregon Hlth & Sci Univ, Oregon Natl Primate Res Ctr, Portland, OR USA.

PLOS PATHOGENS, 2022; 18 (3):

Abstract

The CCR5-specific antibody Leronlimab is being investigated as a novel immunotherapy that can suppress HIV replication with minimal side effects. Here......

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