Discovery of IHMT-MST1-39 as a novel MST1 kinase inhibitor and AMPK activator for the treatment of diabetes mellitus

Wang, JJ; Qi, ZP; Wu, Y; Wang, AL; Liu, QW; Zou, FM; Wang, BL; Qi, S; Cao, JY; Hu, C; Shi, CL; Liang, QM; Wang, L; Liu, J; Wang, WC; Liu, QS

Liu, J; Wang, WC; Liu, QS (通讯作者)，Chinese Acad Sci, Inst Hlth & Med Technol, Hefei Inst Phys Sci, Anhui Prov Key Lab Med Phys & Technol, Hefei 230031, Anhui, Peoples R China.;Liu, QS (通讯作者)，Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China.;Liu, J; Wang, WC; Liu, QS (通讯作者)，Chinese Acad Sci, Hefei Canc Hosp, Hefei 230031, Anhui, Peoples R China.;Liu, QS (通讯作者)，Precis Med Res Lab Anhui Prov, Hefei 230088, Anhui, Peoples R China.

SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023; 8 (1):

Abstract

Insulin-producing pancreatic beta cell death is the fundamental cause of type 1 diabetes (T1D) and a contributing factor to type 2 diabetes (T2D). Mor......

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