Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2

Wines, BD; Kurtovic, L; Trist, HM; Esparon, S; Lopez, E; Chappin, K; Chan, LJ; Mordant, FL; Lee, WS; Gherardin, NA; Patel, SK; Hartley, GE; Pymm, P; Cooney, JP; Beeson, JG; Godfrey, DI; Burrell, LM; van Zelm, MC; Wheatley, AK; Chung, AW; Tham, WH; Subbarao, K; Kent, SJ; Hogarth, PM

Hogarth, PM (通讯作者)，Burnet Inst, Immune Therapies Lab, Melbourne, Vic, Australia.;Hogarth, PM (通讯作者)，Burnet Inst, Life Sci, Melbourne, Vic, Australia.;Hogarth, PM (通讯作者)，Monash Univ, Cent Clin Sch, Dept Immunol & Pathol, Melbourne, Vic, Australia.

FRONTIERS IN IMMUNOLOGY, 2022; 13 ():

Abstract

Joining a function-enhanced Fc-portion of human IgG to the SARS-CoV-2 entry receptor ACE2 produces an antiviral decoy with strain transcending virus n......

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