Fluvastatin attenuated ischemia/reperfusion-induced autophagy and apoptosis in cardiomyocytes through down-regulation HMGB1/TLR4 signaling pathway

Ding, HS; Yang, J; Yang, J; Guo, X; Tang, YH; Huang, Y; Chen, Z; Fan, ZX; Huang, CX

Huang, CX (corresponding author), Wuhan Univ, Renmin Hosp, Dept Cardiol, Wuhan 430060, Peoples R China.; Huang, CX (corresponding author), Wuhan Univ, Inst Cardiovasc Dis, Wuhan 430060, Peoples R China.; Huang, CX (corresponding author), Hubei Key Lab Cardiol, Wuhan 430060, Peoples R China.

MOLECULAR BIOLOGY REPORTS, 2021; 48 (5): 3893

Abstract

Fluvastatin, a traditional fat-decreasing drug, is widely used for curing cardiovascular disease. Previous reports demonstrated that fluvastatin pretr......

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