Dietary ketone body-escalated histone acetylation in megakaryocytes alleviates chemotherapy-induced thrombocytopenia

Xie, SS; Jiang, CY; Wu, M; Ye, Y; Wu, BY; Sun, XT; Lv, X; Chen, RB; Yu, W; Sun, Q; Wu, YT; Que, RL; Li, HL; Yang, L; Liu, W; Zuo, J; Jensen, LD; Huang, GC; Cao, YH; Yang, YL

Yang, YL (通讯作者),Fudan Univ, Sch Basic Med Sci, Dept Cellular & Genet Med, Shanghai 200032, Peoples R China.

SCIENCE TRANSLATIONAL MEDICINE, 2022; 14 (673):

Abstract

Chemotherapy-induced thrombocytopenia (CIT) is a severe complication in patients with cancer that can lead to impaired therapeutic outcome and surviva......

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