Alzheimer's disease brain contains tau fractions with differential prion-like activities

Li, LF; Shi, RR; Gu, JL; Tung, YC; Zhou, Y; Zhou, DW; Wu, RZ; Chu, DD; Jin, NN; Deng, K; Xu, JW; Gong, CX; Iqbal, K; Liu, F

Liu, F (corresponding author), New York State Inst Basic Res Dev Disabil, Dept Neurochem, 1050 Forest Hill Rd, Staten Isl, NY 10314 USA.

ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1):

Abstract

Neurofibrillary tangles (NFTs) made of abnormally hyperphosphorylated tau are a hallmark of Alzheimer's disease (AD) and related tauopathies. Regional......

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