High levels of soluble CD25 in COVID-19 severity suggest a divergence between anti-viral and pro-inflammatory T-cell responses

Xie, M; Yunis, J; Yao, Y; Shi, J; Yang, Y; Zhou, PC; Liang, KL; Wan, YM; Mehdi, A; Chen, ZA; Wang, NQ; Xu, SY; Zhou, M; Yu, MQ; Wang, K; Tao, Y; Zhou, Y; Li, XC; Liu, XS; Yu, X; Wei, YB; Liu, Z; Sprent, J; Yu, D

Xie, M (corresponding author), Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Resp & Crit Care Med, Wuhan, Peoples R China.; Yu, D (corresponding author), Univ Queensland, Diamantina Inst, Fac Med, Brisbane, Qld, Australia.

CLINICAL & TRANSLATIONAL IMMUNOLOGY, 2021; 10 (2):

Abstract

Objectives. We aimed to gain an understanding of the paradox of the immunity in COVID-19 patients with T cells showing both functional defects and hyp......

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