Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method

Gao, YX; Zhang, D; Yang, CY; Duan, XT; Li, XL; Zhong, DF

Li, XL; Zhong, DF (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201210, Peoples R China.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019; 175 ():

Abstract

Establishing reliable bioanalytical methods is essential to support pharmacokinetic (PK) studies in the preclinical and clinical evaluation of monoclo......

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