A Novel d-Peptide Identified by Mirror-Image Phage Display Blocks TIGIT/PVR for Cancer Immunotherapy

Zhou, XM; Zuo, C; Li, WQ; Shi, WW; Zhou, XW; Wang, HF; Chen, SM; Du, JF; Chen, GY; Zhai, WJ; Zhao, WS; Wu, YH; Qi, YM; Liu, L; Gao, YF

Gao, YF (corresponding author), Zhengzhou Univ, Sch Life Sci, Zhengzhou 450001, Peoples R China.; Liu, L (corresponding author), Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Tsinghua Peking Ctr Life Sci,Minist Educ, Beijing 100084, Peoples R China.; Gao, YF (corresponding author), Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Shenzhen 518107, Peoples R China.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020; 59 (35): 15114

Abstract

The low response rate and adaptive resistance of PD-1/PD-L1 blockade demands the studies on novel therapeutic targets for cancer immunotherapy. We dis......

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