Impaired DNA demethylation of C/EBP sites causes premature aging

Schafer, A; Mekker, B; Mallick, M; Vastolo, V; Karaulanov, E; Sebastian, D; von der Lippen, C; Epe, B; Downes, DJ; Scholz, C; Niehrs, C

Schafer, A; Niehrs, C (reprint author), IMB, D-55128 Mainz, Germany.; Niehrs, C (reprint author), Ctr Mol Biol DKFZ ZMBH Allian, German Canc Res Ctr, Div Mol Embryol, D-69120 Heidelberg, Germany.

GENES & DEVELOPMENT, 2018; 32 (11-12): 742

Abstract

Changes in DNA methylation are among the best-documented epigenetic alterations accompanying organismal aging. However, whether and how altered DNA me......

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