Activity-balanced GLP-1/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates

Zhang, YY; Zhao, XY; Dong, XN; Zhang, YY; Zou, HX; Jin, YG; Guo, W; Zhai, P; Chen, X; Kharitonenkov, A

Zhang, YY; Kharitonenkov, A (通讯作者)，Beijing QL Biopharmaceut Co Ltd, Beijing, Peoples R China.

CELL METABOLISM, 2023; 35 (2): 287

Abstract

Obesity is a considerable health concern with limited pharmacotherapy options of low efficacy. Here, we develop a GLP-1/GDF15 fusion protein and explo......

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