Pilot Study of ONCOS-102 and Pembrolizumab: Remodeling of the Tumor Microenvironment and Clinical Outcomes in Anti-PD-1-Resistant Advanced Melanoma

Shoushtari, AN; Olszanski, AJ; Nyakas, M; Hornyak, TJ; Wolchok, JD; Levitsky, V; Kuryk, L; Hansen, TB; Jäderberg, M

Shoushtari, AN (通讯作者),Mem Sloan Kettering Canc Ctr, Dept Med, Melanoma Serv, 200 East 66th St, New York, NY 10065 USA.

CLINICAL CANCER RESEARCH, 2023; 29 (1): 100

Abstract

Purpose: Intratumoral oncolytic virotherapy may overcome anti-PD(L)-1 resistance by triggering pro-inflammatory remo-deling of the tumor microenvironm......

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