CTD: An information-theoretic algorithm to interpret sets of metabolomic and transcriptomic perturbations in the context of graphical models

Thistlethwaite, LR; Petrosyan, V; Li, XQ; Miller, MJ; Elsea, SH; Milosavljevic, A

Milosavljevic, A (corresponding author), Baylor Coll Med, Quantitat & Computat Biosci Program, Houston, TX 77030 USA.; Milosavljevic, A (corresponding author), Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA.

PLOS COMPUTATIONAL BIOLOGY, 2021; 17 (1):

Abstract

We consider the following general family of algorithmic problems that arises in transcriptomics, metabolomics and other fields: given a weighted graph......

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