A thumbwheel mechanism for APOA1 activation of LCAT activity in HDL

Cooke, AL; Morris, J; Melchior, JT; Street, SE; Jerome, WG; Huang, R; Herr, AB; Smith, LE; Segrest, JP; Remaley, AT; Shah, AS; Thompson, TB; Davidson, WS

Davidson, WS (reprint author), Univ Cincinnati, Dept Pathol & Lab Med, Cincinnati, OH 45237 USA.

JOURNAL OF LIPID RESEARCH, 2018; 59 (7): 1244

Abstract

APOA1 is the most abundant protein in HDL. It modulates interactions that affect HDL's cardioprotective functions, in part via its activation of the e......

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