Randomized, double-blind, placebo-controlled phase II study of istiratumab (MM-141) plus nab-paclitaxel and gemcitabine versus nab-paclitaxel and gemcitabine in front-line metastatic pancreatic cancer (CARRIE)

Kundranda, M; Gracian, AC; Zafar, SF; Meiri, E; Bendell, J; Algul, H; Rivera, F; Ahn, ER; Watkins, D; Pelzer, U; Charu, V; Zalutskaya, A; Kuesters, G; Pipas, JM; Santillana, S; Askoxylakis, V; Ko, AH

Ko, AH (corresponding author), Univ Calif San Francisco, Hematol Oncol, POB 0981, San Francisco, CA 94143 USA.

ANNALS OF ONCOLOGY, 2020; 31 (1): 79

Abstract

Background: Preclinical data suggest that dual blockade of the insulin-like growth factor-1 receptor (IGF-1R) and HER3 pathways has superior activity ......

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