Disposition and metabolism of the G protein-coupled receptor 40 agonist TAK-875 (fasiglifam) in rats, dogs, and humans

Kogame, A; Lee, R; Pan, LP; Sudo, M; Nonaka, M; Moriya, Y; Higuchi, T; Tagawa, Y

Kogame, A (reprint author), Axcelead Drug Discovery Partners Inc, Res Div, Drug Disposit & Anal, 26-1 Muraoka Higashi 2 Chome, Fujisawa, Kanagawa 2510012, Japan.

XENOBIOTICA, 2019; 49 (4): 433

Abstract

The absorption, distribution, metabolism, and excretion of fasiglifam were investigated in rats, dogs, and humans. The absolute oral bioavailability o......

Full Text Link