Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo

Boyd, NH; Walker, K; Fried, J; Hackney, JR; McDonald, PC; Benavides, GA; Spina, R; Audia, A; Scott, SE; Libby, CJ; Tran, AN; Bevensee, MO; Griguer, C; Nozell, S; Gillespie, GY; Nabors, B; Bhat, KP; Bar, EE; Darley-Usmar, V; Xu, B; Gordon, E; Cooper,

Hjelmeland, AB (reprint author), Univ Alabama Birmingham, Dept Cell Dev & Integrat Biol, THT 948,1900 Univ Blvd, Birmingham, AL 35294 USA.

JCI INSIGHT, 2017; 2 (24):

Abstract

Tumor microenvironments can promote stem cell maintenance, tumor growth, and therapeutic resistance, findings linked by the tumor-initiating cell hypo......

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