Decreased FXR Agonism in the Bile Acid Pool Is Associated with Impaired FXR Signaling in a Pig Model of Pediatric NAFLD

Maj, MA; Burrin, DG; Manjarín, R

Maj, MA (通讯作者)，Calif Polytech State Univ San Luis Obispo, Dept Biol Sci, San Luis Obispo, CA 93407 USA.;Maj, MA (通讯作者)，Calif Polytech State Univ San Luis Obispo, Ctr Applicat Biotechnol, San Luis Obispo, CA 93407 USA.

BIOMEDICINES, 2023; 11 (12):

Abstract

The objective of this study was to investigate whether the impairment of farnesoid X receptor (FXR)-fibroblast growth factor 19 (FGF19) signaling in j......

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