Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT

Yagci, S; Gozelle, M; Kaya, SG; Ozkan, Y; Aksel, AB; Bakar-Ates, F; Dundar, Y; Eren, G

Eren, G (corresponding author), Gazi Univ, Fac Pharm, Dept Pharmaceut Chem, SIRTeam Grp, TR-06330 Ankara, Turkey.

BIOORGANIC & MEDICINAL CHEMISTRY, 2021; 30 ():

Abstract

Sirtuins (SIRTs) are a class of nicotinamide adenine dinucleotide (NAD+)-dependent protein histone deacetylases (HDACs) that are evolutionarily conser......

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