Assessment of the role of afucosylated glycoforms on thein vitroantibody-dependent phagocytosis activity of an antibody to A beta aggregates

Kwiatkowski, A; Co, C; Kameoka, S; Zhang, A; Coughlin, J; Cameron, T; Chiao, E; Bergelson, S; Mason, CS

Mason, CS (corresponding author), Biogen, Pharmaceut Operat & Technol, Cambridge, MA 02142 USA.

MABS, 2020; 12 (1):

Abstract

The terminal sugars of Fc glycans can influence the Fc-dependent biological activities of monoclonal antibody therapeutics. Afucosylated N-glycans hav......

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