Systemic Immune Modulation in Gliomas: Prognostic Value of Plasma IL-6, YKL-40, and Genetic Variation in YKL-40

Holst, CB; Christensen, IJ; Skjoth-Rasmussen, J; Hamerlik, P; Poulsen, HS; Johansen, JS

Holst, CB (corresponding author), Copenhagen Univ Hosp, Rigshosp, Dept Oncol, Dept Radiat Biol, Copenhagen, Denmark.; Holst, CB (corresponding author), Danish Canc Soc, Danish Canc Soc Res Ctr, Brain Tumor Biol, Copenhagen, Denmark.; Holst, CB (corresponding author), Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Oncol, Herlev, Denmark.; Holst, CB (corresponding author), Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Med, Herlev, Denmark.

FRONTIERS IN ONCOLOGY, 2020; 10 ():

Abstract

Background: Complex local and systemic immune dysfunction in glioblastoma (GBM) may affect survival. Interleukin (IL)-6 and YKL-40 are pleiotropic bio......

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