Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1

Bloch, Y; Bouchareychas, L; Merceron, R; Skladanowska, K; Van den Bossche, L; Detry, S; Govindarajan, S; Elewaut, D; Haerynck, F; Dullaers, M; Adamopoulos, IE; Savvides, SN

Savvides, SN (reprint author), Univ Ghent, Dept Biochem & Microbiol, Lab Prot Biochem & Biomol Engn, B-9052 Ghent, Belgium.; Savvides, SN (reprint author), VIB UGent Ctr Inflammat Res, B-9052 Ghent, Belgium.

IMMUNITY, 2018; 48 (1): 45

Abstract

Interleukin-23 (IL-23), an IL-12 family cytokine, plays pivotal roles in pro-inflammatory T helper 17 cell responses linked to autoimmune and inflamma......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索