Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis The FORWARD Randomized Clinical Trial

Hochberg, MC; Guermazi, A; Guehring, H; Aydemir, A; Wax, S; Fleuranceau-Morel, P; Bihlet, AR; Byrjalsen, I; Andersen, JR; Eckstein, F

Hochberg, MC (reprint author), Univ Maryland, Sch Med, 10 South Pine St,MSTF 8-34, Baltimore, MD 21201 USA.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2019; 322 (14): 1360

Abstract

IMPORTANCE Sprifermin is under investigation as a disease-modifying osteoarthritis drug. OBJECTIVE To evaluate the effects of sprifermin on changes in......

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