Pramipexole inhibits astrocytic NLRP3 inflammasome activation via Drd3-dependent autophagy in a mouse model of Parkinson's disease

Dong, AQ; Yang, YP; Jiang, SM; Yao, XY; Qi, D; Mao, CJ; Cheng, XY; Wang, F; Hu, LF; Liu, CF

Hu, LF; Liu, CF (通讯作者)，Soochow Univ, Dept Neurol, Affiliated Hosp 2, Suzhou 215004, Peoples R China.;Hu, LF; Liu, CF (通讯作者)，Soochow Univ, Clin Res Ctr Neurol Dis, Affiliated Hosp 2, Suzhou 215004, Peoples R China.;Hu, LF; Liu, CF (通讯作者)，Soochow Univ, Jiangsu Key Lab Neuropsychiat Dis, Suzhou 215123, Peoples R China.;Liu, CF (通讯作者)，Xinjiang Med Univ, Dept Neurol, Affiliated Hosp 2, Urumqi 830000, Peoples R China.

ACTA PHARMACOLOGICA SINICA, 2023; 44 (1): 32

Abstract

Inflammation is one of the pathogenic processes in Parkinson's disease (PD). Dopamine receptor agonist pramipexole (PPX) is extensively used for PD tr......

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