The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons

Chua, SW; Cornejo, A; van Eersel, J; Stevens, CH; Vaca, I; Cueto, M; Kassiou, M; Gladbach, A; Macmillan, A; Lewis, L; Whan, R; Ittner, LM

Cornejo, A; Ittner, LM (reprint author), UNSW Australia, Sch Med Sci, Dementia Res Unit, Fac Med, Sydney, NSW 2052, Australia.; Cornejo, A (reprint author), Univ Andres Bello, Med Technol Sch, Fac Med, Santiago 2315, Chile.; Ittner, LM (reprint author), N

ACS CHEMICAL NEUROSCIENCE, 2017; 8 (4): 743

Abstract

In Alzheimer's disease, the microtubule-associated protein tau forms intracellular neurofibrillary tangles (NFTs). A critical step in the formation of......

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