Overexpression of calcitonin gene-related peptide protects mouse cerebral microvascular endothelial cells from high-glucose-induced damage via ERK/HIF-1/VEGF signaling

Guo, YJ; Zhang, Q; Chen, HL; Jiang, YX; Gong, P

Gong, P (reprint author), Sichuan Univ, State Key Lab Oral Dis, Natl Clin Res Ctr Oral Dis, West China Hosp Stomatol, Chengdu, Sichuan, Peoples R China.; Gong, P (reprint author), Sichuan Univ, Dept Implantol, West China Hosp Stomatol, Chengdu, Sichuan, P

JOURNAL OF PHYSIOLOGICAL SCIENCES, 2019; 69 (6): 939

Abstract

In the diabetic brain, hyperglycemia damages the cerebrovasculature and impairs neurovascular crosstalk. Calcitonin gene-related peptide (CGRP) is an ......

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