Repressing IRS1/2 by NT157 inhibits the malignant behaviors of ovarian cancer through inactivating PI3K/AKT/mTOR pathway and inducing autophagy

Li, CX; Men, CD; Yang, WH; Chen, R; Zhu, JH; Cheng, ZP

Cheng, ZP (通讯作者),Tongji Univ, Shanghai Peoples Hosp 10, Dept Gynaecol & Obstet, 301 Yanchang Middle Rd, Shanghai 200072, Peoples R China.

KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2023; 39 (4): 377

Abstract

Insulin receptor substrate 1 and 2 (IRS1/2) have been found involved in many cancers development and their inhibitors exert significant tumor-suppress......

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