A switch of chaperonin function regulates the clearance of solid protein aggregates

Ma, XY; Zhang, M; Ge, L

Ge, L (通讯作者),Tsinghua Univ, Tsinghua Univ Peking Univ Joint Ctr Life Sci, Sch Life Sci, State Key Lab Membrane Biol, Beijing 100084, Peoples R China.;Zhang, M (通讯作者),Tsinghua Univ, Sch Pharmaceut Sci, Beijing 100084, Peoples R China.

AUTOPHAGY, 2022; 18 (11): 2746

Abstract

Protein aggregation is related to many human diseases. Selective macroautophagy/autophagy is the major way to clear protein aggregates in eukaryotic c......

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