LPS-induced inflammation desensitizes hepatocytes to Fas-induced apoptosis through Stat3 activation-The effect can be reversed by ruxolitinib

Markotic, A; Flegar, D; Grcevic, D; Sucur, A; Lalic, H; Turcic, P; Kovacic, N; Lukac, N; Pravdic, D; Vukojevic, K; Cavar, I; Kelava, T

Kelava, T (corresponding author), Univ Zagreb, Sch Med, Dept Physiol, Salata 3, Zagreb 10000, Croatia.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020; 24 (5): 2981

Abstract

Recent studies have established a concept of tumour necrosis factor-alpha (TNF-alpha)/Fas signalling crosstalk, highlighting TNF-alpha as a critical c......

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