Transmembrane TNF-dependent uptake of anti-TNF antibodies

Deora, A; Hegde, S; Lee, J; Choi, CH; Chang, Q; Lee, C; Eaton, L; Tang, H; Wang, D; Lee, D; Michalak, M; Tomlinson, M; Tao, Q; Gaur, N; Harvey, B; McLoughlin, S; Labkovsky, B; Ghayur, T

Deora, A; Hegde, S (reprint author), AbbVie Biores Ctr, Foundat Immunol, 381 Plantat St, Worcester, MA 01605 USA.

MABS, 2017; 9 (4): 680

Abstract

TNF-alpha (TNF), a pro-inflammatory cytokine is synthesized as a 26kDa protein, anchors in the plasma membrane as transmembrane TNF (TmTNF), and is su......

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