Amentoflavone from Selaginella tamariscina as a potent inhibitor of gut bacterial beta-glucuronidase: Inhibition kinetics and molecular dynamics stimulation

Tian, XG; Yan, JK; Sun, CP; Li, JX; Ning, J; Wang, C; Huo, XK; Zhao, WY; Yu, ZL; Feng, L; Lv, X; Ma, XC

Ma, XC (corresponding author), Xuzhou Med Univ, Jiangsu Key Lab New Drug Res & Clin Pharm, Xuzhou, Jiangsu, Peoples R China.; Lv, X (corresponding author), Dalian Med Univ, Dalian Key Lab Metab Target Characterizat & Tradi, Dalian, Peoples R China.

CHEMICO-BIOLOGICAL INTERACTIONS, 2021; 340 ():

Abstract

Gut bacterial beta-glucuronidase (GUS) plays a pivotal role in the metabolism and reactivation of a vast of glucuronide conjugates of both endogenous ......

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