Distinct roles for S. cerevisiae H2A copies in recombination and repeat stability, with a role for H2A.1 threonine 126

House, NCM; Polleys, EJ; Quasem, I; Mejia, MD; Joyce, CE; Takacsi-Nagy, O; Krebs, JE; Fuchs, SM; Freudenreich, CH

Freudenreich, CH (reprint author), Tufts Univ, Dept Biol, Medford, MA 02155 USA.; Freudenreich, CH (reprint author), Tufts Univ, Grad Sch Biomed Sci, Program Genet, Boston, MA 02111 USA.

ELIFE, 2019; 8 ():

Abstract

CAG/CTG trinuncleotide repeats are fragile sequences that when expanded form DNA secondary structures and cause human disease. We evaluated CAG/CTG re......

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