Site-Specific Lipidation Enhances IFITM3 Membrane Interactions and Antiviral Activity

Garst, EH; Lee, H; Das, T; Bhattacharya, S; Percher, A; Wiewiora, R; Witte, IP; Li, YM; Peng, T; Im, W; Hang, HC

Hang, HC (corresponding author), Rockefeller Univ, Lab Chem Biol & Microbial Pathogenesis, New York, NY 10065 USA.; Hang, HC (corresponding author), Scripps Res, Dept Immunol & Microbiol, La Jolla, CA 92037 USA.; Hang, HC (corresponding author), Scripps Res, Dept Chem, La Jolla, CA 92037 USA.

ACS CHEMICAL BIOLOGY, 2021; 16 (5): 844

Abstract

Interferon-induced transmembrane proteins (IFITMs) are S-palmitoylated proteins in vertebrates that restrict a diverse range of viruses. S-palmitoylat......

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