pH-Responsive and liver-targeting drug delivery system for combination delivery of artesunate with arsenic trioxide prodrug against hepatocellular carcinoma

Pan, XW; Huang, JS; Liu, SR; Shao, YD; Xi, JJ; He, RY; Shi, TT; Zhuang, RX; Yu, WY

Zhuang, RX (通讯作者)，Hangzhou Xixi Hosp, Dept Pharmaceut Preparat, 2 Hengbu Rd, Hangzhou 310023, Zhejiang, Peoples R China.;Yu, WY (通讯作者)，Hangzhou Med Coll, Key Lab Neuropsychiat Drug Res Zhejiang Prov, Hangzhou, Peoples R China.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2023; 49 (8): 485

Abstract

ObjectiveArsenic trioxide (ATO) exerts therapeutic effects on various solid tumors, and artesunate (ART) synergizes with antitumor drugs. We herein co......

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